An editorial by Anthony A. Romeo, MD, Chief Medical Editor of Orthopedics Today, describes early orthopaedic clinical research trials and the historic exclusion of women. “This has happened in orthopedics and continues to be a problem today. When a small sample of one sex is included in the analysis or there is no sex-specific analysis, we generalize conclusions to both sexes despite different genetic, hormonal and biomechanically unique strategies to the physical activity or underlying medical disease process,” says Dr. Romeo. Full story.